Tristan Chaplin studies how visual perception translates into spatial perception. When we move through space, our eyes are bombarded with moving visual stimuli from the outside world, and we must collect all this information and piece it together to form coherent picture in order to navigate our way around the environment.
The two brain regions that are likely to play an important role in this process are the primary visual cortex, one of the key visual processing centres of the brain, and the retrosplenial cortex, which is involved in spatial navigation. Dr Chaplin uses 2-photon imaging to characterise the roles of specific cell types that connect these brain regions in freely moving animals. This will have important implications for understanding Alzheimer’s disease, which affects spatial navigation.