Targeting cortical circuit dysfunction to restore movement in Huntington's disease mice
Dr Sonja Blumenstock investigates cortical dysfunctions in Huntington’s disease mice, focusing on how different neuron subtypes are affected as the disease progresses, and how this shapes the animal’s movements. Targeted activation of specific inhibitory neurons rescued movement deficits in mice, pointing to a potential therapeutic target in Huntington's disease. As a winner of the Emerging Neuroscientists Seminar Series, she recently spoke at SWC about her work.