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  • Our research
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  • Study & Work
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Blog

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Blog

Finding the brain’s “real” tuning curves: a SIMPL approach

Place cells fire when an animal enters a specific location. But what happens when an animal just thinks of a location, rather than physically visits the spot? This presents a significant challenge for neuroscientists. SWC PhD student Tom George was determined to help find a way to trace the brain’s “real” tuning curves. Working with colleagues across SWC, the Gatsby Computational Neuroscience Unit and UCL, the team developed a new method called SIMPL.

12 March 2025
Q&A

Bridging senses and disciplines

In this Q&A article, SWC seminar speaker Dr. Jan Gründemann from the German Center for Neurodegenerative Diseases (DZNE) talks about his work to understand how the brain integrates sensory inputs to make memories.

11 March 2025
Blog

Decoding confidence: lessons from the lab

Confidence comes in many forms. Imagine you are lying in bed, and you think you might smell something burning. While you might not be confident about the smell, you are confident you should get up to check. Research led by SWC Group Leader Dr Jeffrey C. Erlich and NYU graduate student Xiaoyue Zhu set out to disentangle the neural mechanisms underlying these different kinds of confidence. 

25 February 2025
Q&A

The do’s and don’ts of publishing in Nature Neuroscience

Following her recent seminar at SWC, Chief Editor of Nature Neuroscience, Shari Wiseman shares her expert advice on positioning research papers for success, debunks common myths about the publication process, and offers a glimpse into the future of scientific publishing.

24 February 2025
Illustration of a mouse on the left with trees on the right some with acorns dotted around near them
Q&A

Neuroscience FoMO: Foraging across Many Options

SWC Emerging Neuroscientists Seminar Series speaker Dr Laura Grima discusses her work with the FoMO setup, and the computational model – AQUA – she is using to describe decision-making. She talks about her findings and the difficulties of science when trying to capture the complexity of life.

21 February 2025
Octagon setup at the Sainsbury Wellcome Centre
Blog

What can mice teach us about football?

Football is adored by fans all around the world. But what makes “the beautiful game” so captivating? Is it the interactive nature, the uncertainty of the outcome, or the complexity of the strategy? All of these elements enticed researchers at the Sainsbury Wellcome Centre to study embodied multi-agent decision-making in a dynamically changing world.

17 February 2025
Blog

Unlocking neural diversity: A new tool for multimodal profiling of brain cell types

SWC researchers have developed a new method, hamFISH, to link gene expression with neuronal connectivity and activity. Using hamFISH they profiled the mouse medial amygdala in unprecedented detail to understand how specific cell types drive behaviour.

14 February 2025
Blog

International Day of Women and Girls in Science

We asked staff at the Sainsbury Wellcome Centre and the Gatsby Computational Neuroscience Unit about their careers, and what it means to them to be a woman in science.

11 February 2025
Q&A

From dawn to dusk: the science behind light and circadian rhythms

The impact of blue light has been a hot topic in the media, but how much should we really worry about its effect on our circadian rhythm? In this Q&A, Professor Peirson shares key findings from his research on the regulation of circadian rhythms and sleep in mammals, discussing implications ranging from jet lag to the design of lighting in the buildings where we spend most of our time.

4 February 2025
Q&A

Decoding motivation: How the brain drives behaviour

Motivation drives nearly all our actions, shaped by a complex interplay of internal needs, external stimuli, and past experiences. In this Q&A, SWC Seminar speaker Dr Andreas Lüthi from the Friedrich Miescher Institute for Biomedical Research talks about his work to explore how brain circuits, particularly in the mouse amygdala, process these factors to influence behaviour.

23 January 2025
Q&A

Could computation connect the origins of life and intelligence?

Many argue that the brain is not a computer, but Blaise Agüera y Arcas challenged this notion in his opening address at the SWC Lecture 2024. He explained how both life and intelligence are inherently computational and may even be selected for in the same way. In this Q&A, Blaise shares more.

16 January 2025
Q&A

Deep RL and the future of AI

Leading AI researcher Professor Jakob Foerster talks about his hopes for the future of AI, its potential to transform research, and his passion for open science in our latest SWC Speaker Q&A.

14 January 2025

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